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Foot Cream A Potential HIV Cure?

A very common anti-fungal drug prescribed to combat toe fungus has been shown in cultures to kill HIV dead. But here's the kicker: unlike anti-virals, HIV doesn't return after use of the medication has been stopped. 

CNET reports:

In a study performed at Rutgers New Jersey Medical School, not only does the drug Ciclopirox completely eradicate infectious HIV from cell cultures, but unlike today's most cutting-edge antiviral treatments, the virus doesn't bounce back when the drug is withheld. This means it may not require a lifetime of use to keep HIV at bay.

The same group of researchers had previously shown that Ciclopirox -- approved by the FDA and Europe's EMA as safe for human use to treat foot fungus -- inhibits the expression of HIV genesin culture. Now they have found that it also blocks the essential function of the mitochondria, which results in the reactivation of the cell's suicide pathway, all while sparing the healthy cells.

The researchers said that one aspect of HIV that makes it particularly persistent, even in the face of strong antiviral treatments, is its ability to disable a cell's altruistic suicide pathway -- which is typically activated when a cell is damaged or infected. In other words, infected cells that would normally commit suicide to spare healthy cells no longer pull any altruistic kamikaze missions. Ciclopirox tricks these cells back into their old ways with a double negative, disabling the disabling of the suicide pathway.

A few commenters have been critical of the potential use to eradicate HIV, claiming that Ciclopirox's topical effects will be unsuccessful in the blood stream. 

What do you think of this potential way to combat the disease? 

(h/t: Joe)

Comments

please help me to thank DR.SAMBOLA for removing HIV sickness in my life,am from Senegal and i have been sick HIV for 9years and i have been visiting hospital for medical check up all to know are vain .it got to a point it got to a point where by i started visiting herbalist for herbs yet the sickness was still distorying my body system there was no changes.i all way share tears from morning till night cos there was no trace of what cause the sickness,medical doctors was unable to detect any thing that was wrong with me and herbalist still try on their own but nothing to write home about.the sickness grow to a stage that i was unable to stand-up on my own except the support of any member of my family and dearth refused to take me away from this painful sickness.one day my either sister who live in united state of America (USA)came with an email and phone number of DR.SAMBOLA that the man have spiritual power that he different problems like this and the one that is even worst than this and i never believed my sister email DR.SAMBOLA about the problem.and DR.SAMBOLA said there is no problem that all we need to do is to perform some sacrifice and cast negative spell off him in his shrine yet i never believed DR.clifford so after performing all the sacrifice DR.SAMBOLA told my sister in 7days time i am going to be heal from this sickness that he has cast out negative spell off me and he has pay 7 sacrifice in seven junction.did you believed that on the 4th day i stand-up on my own to walk without the support of anybody ,before the 7th days i regain all my power in fact i was physically fit.please help me to thank DR.SAMBOLA for removing sickness in my life please if you want to contact him here is the email sambolatemple@gmail.com once again thank you DR.SAMBOLA .EMAIL sambolatemple@gmail.com also kinds of sickness he can help you to cure it okay

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I'm aware that the skin absorbs materials much more than we had been aware. The application shouldnt be oral or even intravenously. To get the proper raming up of dosage to be effective it should be topical or applicable using patch/absorption.

Peggy I'll pray it works for everyone's sake especially your son

I am not sure about using it topically but perhaps if they make this in pill form to get it into the blood stream it will be more effective.

Please let this be true.......i want my son to live

I hope it works too, not only for your son but for all those afflicted, Stay strong and support your son, you obviously love him very much and that in itself is a very powerful medicine.

do you have editors?

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