Jonathan Higbee's picture

Foot Cream A Potential HIV Cure?

A very common anti-fungal drug prescribed to combat toe fungus has been shown in cultures to kill HIV dead. But here's the kicker: unlike anti-virals, HIV doesn't return after use of the medication has been stopped. 

CNET reports:

In a study performed at Rutgers New Jersey Medical School, not only does the drug Ciclopirox completely eradicate infectious HIV from cell cultures, but unlike today's most cutting-edge antiviral treatments, the virus doesn't bounce back when the drug is withheld. This means it may not require a lifetime of use to keep HIV at bay.

The same group of researchers had previously shown that Ciclopirox -- approved by the FDA and Europe's EMA as safe for human use to treat foot fungus -- inhibits the expression of HIV genesin culture. Now they have found that it also blocks the essential function of the mitochondria, which results in the reactivation of the cell's suicide pathway, all while sparing the healthy cells.

The researchers said that one aspect of HIV that makes it particularly persistent, even in the face of strong antiviral treatments, is its ability to disable a cell's altruistic suicide pathway -- which is typically activated when a cell is damaged or infected. In other words, infected cells that would normally commit suicide to spare healthy cells no longer pull any altruistic kamikaze missions. Ciclopirox tricks these cells back into their old ways with a double negative, disabling the disabling of the suicide pathway.

A few commenters have been critical of the potential use to eradicate HIV, claiming that Ciclopirox's topical effects will be unsuccessful in the blood stream. 

What do you think of this potential way to combat the disease? 

(h/t: Joe)


Hi, I work in a communication company I want to share my testimony to the world, my name is maria katrina, i am from united kingdom in belfast north Ireland, I was a stripper in a club I got effected with HIV due to the nature of my job, In April 15 2013 i was tested positive to HIV, Believe it or not this is a true life experience. This is not design to convince you but its just a personal health experience . I never taught doctor ukpoyan could ever get my HIV-AIDS cured with his healing spell, i have tried almost everything but I couldn't find any solution on my disease, despite all these happening to me, i always spend a lot to buy a HIV drugs from hospital and taking some several medications but no relieve, until one day i was just browsing on the internet when i came across a great post of !Michelle! who truly said that she was been diagnose with HIV and was healed that very week through the help of this great powerful healing spell doctor ,I wonder why he is called the great papa ukpoyan, i never knew it was all because of the great and perfect work that he has been doing that is causing all this. so I quickly contacted him, and he ask me some few questions and so i did all the things he asked me to do, He never collected any money from me until I was finally cured, only to see that at the very day which he said i will be healed, all the strength that has left me before rush back and i becomes very strong and healthy, this disease almost kills my life all because of me, so i went to hospital to give the final test to the disease and the doctor said i am HIV negative, i am very amazed and happy about the healing doctor ukpoyan gave to me from the ancient part of africa, you can email him now for your own healing too on his email: thank you doctor for healing me.

I'm aware that the skin absorbs materials much more than we had been aware. The application shouldnt be oral or even intravenously. To get the proper raming up of dosage to be effective it should be topical or applicable using patch/absorption.

Peggy I'll pray it works for everyone's sake especially your son

I am not sure about using it topically but perhaps if they make this in pill form to get it into the blood stream it will be more effective.

Please let this be true.......i want my son to live

I hope it works too, not only for your son but for all those afflicted, Stay strong and support your son, you obviously love him very much and that in itself is a very powerful medicine.

do you have editors?


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