Study: You Can Blame Mom For The Ravaging Physical Effects Of Aging
We're total and notorious mama's boys, but if mom's the main reason our Botox budget warrants an increase every six months, then we might have to start pointing some wrinkled, liver-spotted fingers.
According to a new study published in the journal Nature, the way that you will physically be affected by aging is largely due to genes from your mother.
There are many causes of aging that are determined by an accumulation of various kinds of changes that impair the function of bodily organs. Of particular importance in aging, however, seems to be the changes that occur in the cell's power plant -- the mitochondrion. This structure is located in the cell and generates most of the cell's supply of ATP which is used as a source of chemical energy.
"The mitochondria contains their own DNA, which changes more than the DNA in the nucleus, and this has a significant impact on the aging process," said Nils-Göran Larsson, Ph.D., professor at the Karolinska Institutet and principal investigator at the Max Planck Institute for Biology of Aging, and leader of the current study alongside Lars Olson, Ph.D., professor in the Department of Neuroscience at the Karolinska Institutet. "Many mutations in the mitochondria gradually dis-able the cell's energy production," said Larsson.
For the first time, the researchers have shown that the aging process is influenced not only by the accumulation of mitochondrial DNA damage during a person's lifetime, but also by the inherited DNA from their mothers.
Mom has always blamed us for gray hair and wrinkles. Now we can do the same.
"Surprisingly, we also show that our mother's mitochondrial DNA seems to influence our own aging," said Larsson. "If we inherit mDNA with mutations from our mother, we age more quickly."