HIV

New Antibody Attacks 99% of HIV Strains

Image via Pexels

Scientists have created a new antibody that not only recognizes and fights 99% of HIV strains, but early tests are also showing its ability to prevent infection.

This new antibody is the work of both the US National Institutes of Health and the pharmaceutical company Sanofi.

Together, the two groups have released the results of a study they’ve been conducting with the antibody.

To understand the way the antibody works you have to first understand that the real problem for treating HIV is.

HIV is ever changing. HIV’s composition can change and mutate constantly and these varying HIV “strains” makes it hard to combat the disease. If you target one strain, there will be an insurmountable amount of varying strains still standing in its place.

That said, throughout the decades there have been cases of people naturally developing what’s called “broadly neutralizing antibodies” that are able to kill several different kinds of HIV strains.

Scientists from both the US National Institutes of Health and the company Sanofi have combined samples of these anitbodies into what they call the “tri-specific antibody” and have developed it to attack three critical parts of the virus.

Scientists and researchers around the globe are celebrating the discovery and praising those involved.

Dr. Gary Nabel / Image via Nih Record

Prof Linda-Gail Bekker, the president of the International Aids Society, told the BBC News:

 "This paper reports an exciting breakthrough.”

"These super-engineered antibodies seem to go beyond the natural and could have more applications than we have imagined to date.”

"It's early days yet, and as a scientist I look forward to seeing the first trials get off the ground in 2018.”

"As a doctor in Africa, I feel the urgency to confirm these findings in humans as soon as possible."

In addition, Dr Gary Nabel, the chief scientific officer for Sanofi, also spoke to BBC about the antibody, "They are more potent and have greater breadth than any single naturally occurring antibody that's been discovered."

"We're getting 99% coverage, and getting coverage at very low concentrations of the antibody," said Dr Nabel.

The bulk of the earlier study was administered on 24 monkeys, with none of the ones who received the tri-specific antibodies getting infected with HIV, but now that that study was a success clinical studies on humans can commence sometime next year.

Daddybear App Issues Apology For Its Anti-Men With HIV Message

Image via Pexels

Last month, the new dating app DaddyBear came onto the gay scene with a big splash, but it wasn’t in a good way.

As soon as the sugar daddy app released its first press release and opened its doors for business, gay sites, like Instinct, were criticizing it for its stance on men living with HIV. Essentially, the idea the app was presenting is that gay men want to remain healthy, so it would only cater to people who didn’t have a positive HIV status.

While it’s understandable for gay men wanting to remain STD/STI and HIV free, the app was ostracizing men living with HIV and increasing the stigmatism against them. The app added to the idea of dehumanizing men living with HIV and seeing them as just harbingers for the disease.

That’s why so many people were against the DaddyBear app. And it seems the powers behind the app may have listened.

The team behind DaddyBear have just released to the press an apology for the initial mindset the app held. They did this by first stating the turn of events (initial release, widespread criticism, and eventual reflection).

From there, the press release talks about the app’s creator Justin (whose last name has been withheld), his romantic history, and why he first thought of creating the app.

“As for this improper idea, it came for a reason. Justin is a gay sugar daddy who is loyal and prefers long term relationships. His last partner left him for no reason and he has had a really hard time to accept that breakup. Recently, Justin heard that his partner was infected with HIV during their relationship when he was having unprotected sex with another guy who was with the malicious intent to transmit the disease. After diagnosed, his partner felt ashamed and desperate, so he chose to put an end to the relationship. Although Justin couldn’t forgive his betrayal, he was so mad at the guy who infected his partner. That anger lead him to wrongly misjudge the present situation and make an immature decision to build a gay dating app that doesn’t allow gay men living with HIV.”

Image via DaddyBear on Itunes

The press release then goes into explaining how Justin has reflected and realized that HIV men are living comfortably in modern times.

“We realized that there are many hiv positive guys out there and most of them are receiving systematic treatment which can help them have an undetectable viral load and highly prevent HIV transmission.”

Then the press release thanked writers of gay sites, like Mark S. Knight, for criticizing the original app.

But what the press release fails to mention now is if it will really change after the fact. The letter ended stating, “DaddyBear is a great gay dating app for gay sugar daddies, gay sugar babies and all gay men,” but how will DaddyBear rework its advertisements and “healthy only” perspective?

While the letter seems apologetic and sincere, it did not outright state any plans to change. Plans of change are implied by the fact this is an apology, but it’s not stated.

And adding to that, the original story brings up more questions. For instance, why not state that inciting incident was the catalyst of this app from the get-go? That could have at least doused some of the flames from the app’s release.

But then, the story also complicates things. Ultimately, it’s the story of someone feeling hurt from a breakup and blaming all men living with HIV for the acts of a single man. Of course, many initiatives have been started for similarly stupid and close minded acts, but knowing the story behind this one makes the app seem even more pitiful.

So, while it’s nice to hear that DaddyBear acknowledges that many people were upset with its initial response. We have to see if the app will really change its mindset in the next few months.

Though, are any of us even using it to begin with?

Ryan Murphy Says American Crime Story: Versace Will Tackle His HIV Status

Ryan Murphy / Credit: Hollywood Reporter

We’re all looking forward to American Crime Story: The Assassination of Gianni Versace because of its stellar cast.

Not only is Penelope Cruz stunning in her role's costume, but the men of the show are already giving us a great show. From Darren Criss in a red speedo to Ricky Martin dazzling all (but Versace’s real life lover) in the role.

But what we should all be really looking forward to is a real, or at least close enough knowing Hollywood, depiction of Gianni Versace’s life and death.

Of course, with someone like Ryan Murphy at the reigns, it could be 50/50 either way.

But, while speaking at a recent Television Critics Association summer conference meeting, Murphy assured the audience that the show is going for believability and historical facts.

“We’ve spoken to other people who have definite ideas about what was going on with him at the time,” he said while at the head of the conference, “I think we’ve been very respectful to his family, particularly. Donatella had some requests about how the children were depicted in the show. I listened to that. As a father, I understood. I wasn’t interested in going there, out of respect for her.”

In addition, Ryan Murphy wanted to express the fact that the series will also focus on Versace’s HIV status. At the time, the designer was very secretive about the fact due to the public’s mentality around HIV, but, again, Murphy wanted to go for truth and facts in his depiction despite the stigma.

“You could literally lose your business, lose everything that you had,” he said. “Versace’s company was about to go public, and he was terrified of anything negative coming out about his personal life. We delve into that in the show.”

So, knowing that Murphy is going for an honest depiction, are you more interested in the show then you were before?

New Dating App For Sugar Daddies Is Cover-Up For Discrimination

There’s a new sugar daddy app out that’s already getting some heat for the way that it’s marketing itself.

On a first glance, DaddyBear is just the newest in an ongoing tide of gay dating apps and sugar daddy websites.

And in a time where several gay men are finding their own sugar daddy to help pay off debt and college loans, this isn’t something we’d usually turn twice for. But, there’s something different about DaddyBear.

Again, at first DaddyBear doesn’t seem like much with the tagline, “It offers all the possibilities for wealthy gay daddies and healthy gay men or bears.”

But once you stop to think a second or reread the line you notice the words “healthy gay men.” Interesting.

Then, if you visit the website version of the app, you’ll find an interesting description of what the site offers its users.

“Gay Daddies can share sexual experiences with you and help find out your special identity, because they have more life experiences to help you explore more new areas you never know.”

“Most mature gay daddies grew up under the macro environment of AIDS epidemic and scare, so they know how to protect themselves and you, and enjoy safe sex with you.”

It then goes further to state (and this is word for word):

“Gay Daddies are successful or rich men who have more money and social wealth than you do. They did never marry and will life with you without kids, so they must be happy to give you more support and help including your occupational plan.”

Of course, all of this (badly worded) rhetoric raised red flags for several members of the gay community. For instance, Matthew Hodson, the Executive Director of HIV advocacy and education organization NAM spoke to GayStarNews and said:

“People with HIV on treatment now have a near normal life expectancy. What’s more, effective HIV treatment means we can’t pass the virus on to our sexual partners. The greatest challenge for many people living with HIV now is dealing with HIV stigma, which is fueled by outdated attitudes, ignorance and fear.”

“Almost every person I know who lives openly with HIV has been rejected because of their status. People are often shamed and insulted on dating apps if they disclose. I fear that apps for ‘healthy gay men’ may encourage these attitudes.”

At this point, you could say that DaddyBear is discriminating against people living with HIV.

And, as if all of this wasn’t bad enough, DaddyBear had to get its own word into the conversation. You see, at the top of the comments on GayStarNews’ article on the topic, a representative of DaddyBear (using the Facebook account of the app) commented with the following statement:

“We highly appreciate that you have shared DaddyBear app…

With the fact that most gay men care more about health than sex when seeking gay relationship, we create this gay dating app to meet their needs. If you are worried about meeting gay men who are living with HIV, then you can feel relieved with our App because we are trying our best to make sure that all users you meet will be healthy and without HIV, starting from adding a feature to allow users to verify their health condition.”

Now don’t get me wrong, I understand the desire to not have a surprise when it comes to STDs. That said, this site and app is ultimately pushing the stigma that people living with HIV are to be avoided and are “unhealthy.”

Look, it’s your choice if you want to use this app or not. And I understand if the words being used by DaddyBear appeals to any one of you. But at the end of the day, it’s discrimination and we all need to recognize that.

While some might think, “Why give a spotlight to it then?” I say we should know about the wrong being done so that then we can work to fix it. Recognize discrimination and don’t put your money behind such apps.

But that’s just this author’s two cents (the only money I’ll ever throw at this company).

The HIV Generation Gap

Picture of Tyler Curry (@iamtylercurry) courtesy of  Kevin Chung

 

For the past 30 years, gay men have been stuck in a constant sparring match with HIV. For the first two decades of the epidemic, it seemed that we could never measure up to the brute and brawn of this vile disease. But in the third decade of battle, it appears that we are primed for one of the greatest comebacks of all time. This potential victory comes with great loss. Some of our best men who were a part of the initial rounds were knocked out of the battle far too early. Entire communities were ravaged by this ominous foe, leaving only a few where there were once many still standing. Now, these veteran survivors stand along with many new fighters in the battle, but sometimes there is strife within the differing ranks.

Of course, it is to be expected that those who have been a part of the fight since the beginning will have a deeper connection and sense of ownership with their forever "shadow boxer." As these men tell the tales of a time of more funerals than birthday parties, early meds that made you want to die and the hope of just living another year, maybe two, it hardly seems like we are in the same battle at all.

Men like Peter Staley, Mark S. King and Jack Mackenroth and many others paved the road for people like Chris Richey and Scott McPherson of the Stigma Project and myself to enter the ring with a much lesser foe today. These veteran fighters as well as many others have served as mentors for us. They are patient, forgiving and kind as we stumble around, finding our footing in the world of activism.

But just like in any battle, some of these long-term survivors can sometimes hold a bit of resentment toward those who avoided the worst part of the fight. And this sentiment is quite understandable.

The early days of HIV are comparable to very few other epidemics in modern history. Unlike other health crises, an additional layer of shame and blame were included in the symptoms that accompanied the virus. These people were shunned for more than just the fear of infection and were often left alone to face the certainty of death. For the men and women who somehow outlasted their dismal prognosis, and to the many others who fortuitously avoided infection, the pain of losing so many others to the disease is still palpable.

For some, this pain has hardened into a tear-tinged anger toward younger men who are diagnosed today. It can be easy to view these newbies as privileged morons instead of the unknowing victims of the early years. An angry finger is wagged at the newly diagnosed twentysomething who assumedly threw caution to the wind, because any gay men with half a brain knows exactly how HIV is transmitted.

How could these young men not know? Or is HIV considered so easily managed that the younger generation just doesn’t care anymore? The mere possibility of these questions being true is enough to send some long-term survivors into a chastising tirade, complete with a barrage of scary (and out-of-date) side effects, judgmental labels and a healthy serving of shame...just like they received all those years ago.

Although the emotion behind these actions is understandable, the delivery only serves to perpetuate the fear and silence that only helps to increase transmission rates.

As someone who is newly HIV-positive myself, I can only sympathize with long-term survivors of the disease. I would dare not say I could empathize. I will never know how it must have felt to discover you were carrying a death sentence in your bloodstream. I shudder to even imagine having to see my friends waste away around me or to experience the horrendous side effects that were often worse that the disease itself.

And although modern medicine has eradicated the eminent doom that so many gay men from the early years had to face, the stigma that kept so many quiet about their disease is still alive and well. It is within this stigma that you can find the root to a myriad of psychological issues that lead to young, naïve gay men to become infected today.

I know this all too well. Only a year ago, I was unaware that anyone in my immediate social web was living with HIV. They were all too afraid of the judgment that comes attached to the positive label. It was only after I began to bang my drum and call attention to my status that so many around me revealed that they too were living with the disease.

The drastically different generational experiences with HIV can make it almost feel like we are sometimes on opposite sides of the ring. But whether veteran or novice, there is a common vein of shame and stigma that we feel in the fight of HIV. The fighting style of our opponent has changed, and the new fighters must rely on the survivors of the fight to help us keep up the winning streak.

Our bodies are solid. But we need the veterans to help us new fighters strengthen something else.

Our voices.

 

HIV Victims and Villains: Who Is Really At Fault?

Picture of Tyler Curry (@iamtylercurry) courtesy of  Kevin Chung

 

There is a common assumption among the sexually active homo population that it is the responsibility of HIV-positive men to disclose their status before engaging in bedroom gymnastics. Based on this assumption, a person who doesn’t mention his status before he tries and fails to make a baby with another man silently asserts that he is HIV-negative by default. Even if a person living with HIV is undetectable and protection was used, he would be considered reprehensible, immoral and altogether villainous character if he failed to disclose his scarlet plus sign to his unknowing HIV-negative partner. But when it comes to the laws of responsibility in HIV disclosure, sometimes there is more than one suspect in a crime.  

The Scene of the Crime

The following scenario is based on a true story

Parker is a young, successful and single gay man living with HIV. Nathan is of the same homo vein, but he is HIV-negative. The two met while Parker was at a business conference and Nathan was on vacation with several of his friends. A mojito at the hotel pool quickly led to martinis at the closest gay bar. Dinner was served, flirtation escalated and Nathan ended up back in Parker’s room for a little more than dessert. The fast and frenzied pace of this out-of-town romance caught Parker by surprise and he failed to find the right moment to disclose his HIV status (and Nathan never asked). His viral load was at an undetectable level and they used protection, but his conscience wasn’t satisfied with this threshold of safety. 

The Confession

Parker and Nathan parted ways the next morning with plans to meet up for a drink later in the day.  By six o’clock, the weight of the guilt over not disclosing had Parker in need of more than just a strong pour on his vodka gimlet. He needed to clear the air. 

Parker told Nathan that he was HIV positive. He explained that he was on medication and had an undetectable viral load. He said that since they used a condom, his health was not at risk, but that it was important for Parker to be honest about his status. 

Nathan was visibly shaken and admitted that Parker should have disclosed his status before they had sex. He was concerned because there was a lot of kissing and oral play that took place.  Parker explained the reality of transmission and that Nathan had nothing to worry about, but the damage was done. Nathan felt victimized and he was sitting across from the smoking gun.  Needless to say, the two men didn’t order a second round.

For the jury of public opinion, the judgment of who committed the crime and who was the victim receives a unanimous vote. But before the sentence of shame is handed down to Parker for not disclosing his status, let’s look at who had the motive to commit the crime. 

Parker did want to tell Nathan about his HIV status. As a man who was actively managing his disease with treatment, it was important for him to be up front about being positive, even if there was no health risk involved. However, many people fail to understand that when you become positive, you aren’t handed an operator’s guide on how to handle your new status. The variables of sexual psychology are limitless when concerning dating and HIV. Although he failed to disclose that he was a positive man, he had taken the steps to protect Nathan and himself—both by using a condom and being steadfast in his treatment regime. 

Nathan is a sexually active gay man who, by default, is part of the HIV community. With one out of every five gay males being HIV positive, it is his responsibility to protect his own sexual health.  It’s true—Parker did not disclose that he is HIV positive. But Nathan didn’t disclose that he was HIV negative, nor did he ask to know Parker’s status before the clothes started to come off. In this scenario, Nathan has a motive to stay negative. Therefore, he is also guilty of committing a crime of not disclosing his status and not inquiring about the status of his sexual partner.

This is only one out of many criminal scenarios that many of us find ourselves in when it comes to dating, dirty talk and disclosure. When it comes to sex, there are always two (or more) suspects whose motives should be investigated. And when it comes to protecting each other’s health, the burden is mutually shared and the responsibility is equally divisible, regardless of status.

I always disclose my HIV-positive status because it is in the best interests of my health, not yours.