A third person to have contracted HIV while on PrEP. According to findings from Dr. Elske Hoornenborg from Seattle, the 50-years old Dutch man was taking PrEP daily and kept a diary of his sexual activity (over 50 men a month) on a phone app. Hoornenborg theorized a small level of the virus may have stayed in his rectum.
Without his knowledge before it had a chance to spread throughout the body. Because of this, even a small dip of Truvada concentration in his rectum that may have occurred without another corresponding drop in blood levels may have given HIV a small opportunity to spread. The two drugs in Truvada (tenofovir disproxil fumarate/emtricitabine) may not have been enough to fight against such a unique circumstance.
[The Dutch man kept track of his sexual partners in his diary. He] reported to have have sex with 75 partners the first month, 56 the second month, 56 the third month, 50 the fourth, 38 the fifth, 49 the sixth, and 66 the seventh, with 12 anal sex partners in total.
According to questionnaires, the man had barrier free anal sex with 90 partners during the first 12 weeks. During the duration of the study, while he was on PrEP, he was diagnosed twice with rectal gonorrhea and once with rectal Chlamydia. – hivplusmag.com
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