Bye Prozac? Hello K! Ketamine Being Fast Tracked By FDA For Depression Treatment.

Have you had to drag a friend out of a club and out of a k-hole?  Have you had others that have suffered from severe depression?  The FDA is now looking into where these two may overlap.  Ketamine is being fast tracked for approval as a treatment of depression.  Bye bye Prozac?

If you are suffering from depression, there may be a promising new treatment on the horizon. The catch? You have to be OK with taking the party drug, Ketamine.

Apparently, the Food and Drug Administration (FDA) has put esketamine, a derivate of Ketamine, on the fast track for approval to treat Major Depressive Disorder. The announcement came yesterday from Janssen Pharmaceutical, a Johnson and Johnson company.

Designated as a “breakthrough” therapy, the drug would offer psychiatrists a new method for quickly helping people who have suicidal tendencies.

If all goes according to plan, esketamine would be the first drug approved for Major Depressive Disorder in half a century. Currently, many doctors prescribe selective serotonin reuptake inhibitors (SSRIs), like Zoloft and Prozac, as pathways to treatment.

The problem with ketamine as a potential treatment modality is that historically, the drug has been linked to people who “party”. Referred to by some as simply “K”,  ketamine has been tied to date rapes and other situations involving foul play.

Many people describe the experience of being on ketamine as dissociative. In some recreational drug taking circles, this out of body “high” is referred to as a “K-Hole.” This makes sense when you consider that ketamine is currently used as a form of anesthesia. –

For more on this, head over to where they mention two tests that are being done, the major benefit of Esketamine (how incredibly fast it works), where the drug may be able to be administered, and the possible side effects.

These are not new thoughts, K and its derivates helping out depression, but it is new that the FDA is catching on to what scientists have known for years.


Would you be willing to use Esketamine to help your depression?



Currently, suicide is ranked as the tenth leading cause of death in the United States with approximately 41,000 people taking their own lives each year according to the CDC.

Within the LGBT community, depression is a going concern. While the statistics are somewhat scattered, the current research suggests that depression affects LGBT people at a higher rate when compared to their heterosexual counterparts. –




What do you think?